Sustaining optimal health and well-being requires the contribution of multiple sectors and the role of environment sector is indispensable to the attainment of the same. Different types of hazards have been attributed to microplastics, based on the extent and route of exposure. There is an indispensable need to optimize the existing waste-water and drinking-water treatment systems, as this can significantly minimize the concentration of these harmful substances. In conclusion, humans have been exposed to microplastics through a wide range of sources. Acknowledging the fact that plastics in themselves are potential threats for climate deterioration and health hazards, it is high time that adequate focus should be given towards their reduction in production and optimal treatment to eventually minimize the health risks.